BU 224 hydrochloride

CAS No. 205437-64-5

BU 224 hydrochloride ( —— )

Catalog No. M27501 CAS No. 205437-64-5

BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 Get Quote
5MG 72 Get Quote
10MG 110 Get Quote
25MG 237 Get Quote
50MG 380 Get Quote
100MG 550 Get Quote
500MG 1161 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    BU 224 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
  • Description
    BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.(In Vivo):BU 224 hydrochloride (5 mg/kg; i.p.) attenuated spatial and perirhinal cortex-dependent recognition memory deficits in 5XFAD mice. Fear-conditioning testing revealed that BU 224 hydrochloride also improved both associative learning and hippocampal- and amygdala-dependent memory in transgenic but not in WT mice. In the brain, BU 224 hydrochloride reduced levels of the microglial marker Iba1 and pro-inflammatory cytokines IL-1β and TNF-α and increased the expression of astrocytic marker GFAP in 5XFAD mice.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    205437-64-5
  • Formula Weight
    233.7
  • Molecular Formula
    C12H12ClN3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mahanta S, et al. Sour beer production in India using a coculture of Saccharomyces pastorianus and Lactobacillus plantarum: optimization, microbiological, and biochemical profiling. Braz J Microbiol. 2022 Jun;53(2):947-958.
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