BU 224 hydrochloride
CAS No. 205437-64-5
BU 224 hydrochloride ( —— )
Catalog No. M27501 CAS No. 205437-64-5
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 43 | Get Quote |
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5MG | 72 | Get Quote |
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10MG | 110 | Get Quote |
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25MG | 237 | Get Quote |
|
50MG | 380 | Get Quote |
|
100MG | 550 | Get Quote |
|
500MG | 1161 | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameBU 224 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
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DescriptionBU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.(In Vivo):BU 224 hydrochloride (5 mg/kg; i.p.) attenuated spatial and perirhinal cortex-dependent recognition memory deficits in 5XFAD mice. Fear-conditioning testing revealed that BU 224 hydrochloride also improved both associative learning and hippocampal- and amygdala-dependent memory in transgenic but not in WT mice. In the brain, BU 224 hydrochloride reduced levels of the microglial marker Iba1 and pro-inflammatory cytokines IL-1β and TNF-α and increased the expression of astrocytic marker GFAP in 5XFAD mice.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number205437-64-5
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Formula Weight233.7
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Molecular FormulaC12H12ClN3
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mahanta S, et al. Sour beer production in India using a coculture of Saccharomyces pastorianus and Lactobacillus plantarum: optimization, microbiological, and biochemical profiling. Braz J Microbiol. 2022 Jun;53(2):947-958.
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